Motif ID: RXRA_VDR{dimer}.p2

Z-value: 0.504


Transcription factors associated with RXRA_VDR{dimer}.p2:

Gene SymbolEntrez IDGene Name
VDR 7421 vitamin D (1,25- dihydroxyvitamin D3) receptor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
VDRchr12_-_482987650.202.8e-01Click!


Activity profile for motif RXRA_VDR{dimer}.p2.

activity profile for motif RXRA_VDR{dimer}.p2


Sorted Z-values histogram for motif RXRA_VDR{dimer}.p2

Sorted Z-values for motif RXRA_VDR{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RXRA_VDR{dimer}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_34419957 0.958 NM_022073
EGLN3
egl nine homolog 3 (C. elegans)
chr17_-_34756980 0.840 NM_001123392
TBC1D3C
TBC1D3G
TBC1D3
TBC1D3H
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3
TBC1 domain family, member 3H
chr17_-_36348585 0.806 NM_001123391
NM_032258
TBC1D3C
TBC1D3
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3
TBC1 domain family, member 3F
chr17_+_36283959 0.796 NM_001123391
NM_032258
TBC1D3C
TBC1D3
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3
TBC1 domain family, member 3F
chr3_-_59035700 0.755 NM_198463
C3orf67
chromosome 3 open reading frame 67
chr17_-_34591958 0.750 NM_001001418
TBC1D3C
TBC1D3G
TBC1 domain family, member 3C
TBC1 domain family, member 3G
chr7_+_143701021 0.700 NM_001005281
OR6B1
olfactory receptor, family 6, subfamily B, member 1
chr17_-_34503914 0.652 NM_001001417
TBC1D3B
TBC1D3C
TBC1D3G
TBC1 domain family, member 3B
TBC1 domain family, member 3C
TBC1 domain family, member 3G
chr13_+_114321469 0.645 NM_002929
GRK1
G protein-coupled receptor kinase 1
chr14_+_55168831 0.612 SAMD4A
sterile alpha motif domain containing 4A
chr3_-_54961961 0.596 NM_020678
LRTM1
leucine-rich repeats and transmembrane domains 1
chr22_+_50624353 0.486 NM_025204
TRABD
TraB domain containing
chr8_+_10383055 0.415 NM_001197020
NM_198464
PRSS55

protease, serine, 55

chr15_-_89764809 0.414 NM_000326
RLBP1
retinaldehyde binding protein 1
chr22_+_50624267 0.409 TRABD
TraB domain containing
chr1_+_47137496 0.403 NM_001145474
ATPAF1-AS1
ATPAF1 antisense RNA 1 (non-protein coding)
chr20_-_52790511 0.385 NM_000782
NM_001128915
CYP24A1

cytochrome P450, family 24, subfamily A, polypeptide 1

chr7_+_155089614 0.385 INSIG1
insulin induced gene 1
chr17_+_2699731 0.375 NM_001100398
NM_015085
RAP1GAP2

RAP1 GTPase activating protein 2

chrX_+_106161589 0.329 NM_001171095
CLDN2
claudin 2
chr9_+_131644780 0.321 NM_001127244
LRRC8A
leucine rich repeat containing 8 family, member A
chr16_+_28889808 0.309 NM_004320
NM_173201
ATP2A1

ATPase, Ca++ transporting, cardiac muscle, fast twitch 1

chr19_+_589849 0.308 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr17_-_39216343 0.307 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr11_+_73087670 0.303 NM_032871
RELT
RELT tumor necrosis factor receptor
chr8_-_8239188 0.293 NM_001080826
SGK223
homolog of rat pragma of Rnd2
chr19_+_42817434 0.292 NM_173633
TMEM145
transmembrane protein 145
chr8_+_76320106 0.291 HNF4G
hepatocyte nuclear factor 4, gamma
chr12_-_6579754 0.282 NM_014231
NM_016830
NM_199245
VAMP1


vesicle-associated membrane protein 1 (synaptobrevin 1)


chr21_-_47575472 0.273 NM_006657
NM_206965
FTCD

formiminotransferase cyclodeaminase

chr19_-_36399205 0.265 NM_001173514
NM_001173515
NM_003332
NM_198125
TYROBP



TYRO protein tyrosine kinase binding protein



chr2_+_238768186 0.257 NM_005855
RAMP1
receptor (G protein-coupled) activity modifying protein 1
chr19_-_36399120 0.252 TYROBP
TYRO protein tyrosine kinase binding protein
chr12_-_109251333 0.245 NM_001161330
NM_018984
SSH1

slingshot homolog 1 (Drosophila)

chr14_-_101034261 0.243 NM_001159531
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr20_-_34195409 0.238 FER1L4
fer-1-like 4 (C. elegans) pseudogene
chr6_+_151646634 0.238 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr19_-_36399183 0.236 TYROBP
TYRO protein tyrosine kinase binding protein
chr19_-_51472003 0.231 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr19_+_56186426 0.229 NM_001130072
NM_013333
EPN1

epsin 1

chr1_+_226736500 0.226 NM_001003665
C1orf95
chromosome 1 open reading frame 95
chr6_-_68598987 0.223 ERVH-3
endogenous retrovirus group H, member 3
chr8_-_93115453 0.222 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr1_-_205325915 0.217 NM_018203
KLHDC8A
kelch domain containing 8A
chr11_-_790103 0.215 NM_016564
CEND1
cell cycle exit and neuronal differentiation 1
chr20_-_39946119 0.206 ZHX3
zinc fingers and homeoboxes 3
chr9_+_139839697 0.199 NM_000606
C8G
complement component 8, gamma polypeptide
chr19_-_58858900 0.198 A1BG
alpha-1-B glycoprotein
chr19_+_56186580 0.193 EPN1
epsin 1
chr22_+_18593556 0.192 TUBA8
tubulin, alpha 8
chr17_-_72855884 0.187 NM_000835
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr9_+_131798899 0.185 FAM73B
family with sequence similarity 73, member B
chr19_+_56186569 0.184 EPN1
epsin 1
chr7_+_128577990 0.183 NM_001098629
NM_001098630
NM_001242452
IRF5


interferon regulatory factor 5


chr17_-_56609361 0.178 SEPT4
septin 4
chr12_+_57610577 0.176 NM_007224
NXPH4
neurexophilin 4
chr15_-_73661141 0.175 HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr2_+_220462560 0.173 NM_052902
STK11IP
serine/threonine kinase 11 interacting protein
chr7_+_155089483 0.173 NM_005542
NM_198336
NM_198337
INSIG1


insulin induced gene 1


chr10_+_11047253 0.169 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr6_+_38683116 0.165 NM_001206927
DNAH8
dynein, axonemal, heavy chain 8
chr14_-_65289812 0.164 NM_000347
NM_001024858
SPTB

spectrin, beta, erythrocytic

chr17_+_65373574 0.161 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr2_+_223289212 0.156 SGPP2
sphingosine-1-phosphate phosphatase 2
chr17_+_65373362 0.154 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr16_+_31119730 0.152 BCKDK
branched chain ketoacid dehydrogenase kinase
chr17_-_64225496 0.145 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr19_+_50270263 0.145 AP2A1
adaptor-related protein complex 2, alpha 1 subunit
chr19_+_56186610 0.138 EPN1
epsin 1
chr16_+_14726828 0.136 BFAR
bifunctional apoptosis regulator
chr9_+_35673852 0.133 NM_001216
CA9
carbonic anhydrase IX
chr16_+_31119661 0.133 NM_001122957
NM_005881
BCKDK

branched chain ketoacid dehydrogenase kinase

chr18_-_59560303 0.132 NM_173557
RNF152
ring finger protein 152
chr10_+_80899458 0.132 ZMIZ1
zinc finger, MIZ-type containing 1
chr1_-_27732069 0.129 WASF2
WAS protein family, member 2
chr7_+_128578246 0.129 NM_032643
IRF5
interferon regulatory factor 5
chr19_-_51472816 0.127 NM_002774
KLK6
kallikrein-related peptidase 6
chr1_+_229406835 0.127 NM_004578
RAB4A
RAB4A, member RAS oncogene family
chr18_+_48086402 0.126 NM_002747
MAPK4
mitogen-activated protein kinase 4
chr11_+_64126616 0.124 NM_001006944
NM_003942
RPS6KA4

ribosomal protein S6 kinase, 90kDa, polypeptide 4

chr14_+_94640648 0.123 NM_020958
NM_058237
PPP4R4

protein phosphatase 4, regulatory subunit 4

chr2_+_223289285 0.122 NM_152386
SGPP2
sphingosine-1-phosphate phosphatase 2
chr12_+_52627007 0.121 KRT7
keratin 7
chr18_+_77623667 0.119 NM_012283
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr1_-_154943001 0.118 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr17_-_39222126 0.118 NM_033184
KRTAP2-4
keratin associated protein 2-4
chr3_-_49142165 0.111 NM_005051
QARS
glutaminyl-tRNA synthetase
chr1_-_201081693 0.111 NM_000069
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr16_-_31105922 0.110


chr19_-_49552362 0.110 NM_033183
CGB8
chorionic gonadotropin, beta polypeptide 8
chrX_+_153686620 0.109 NM_017514
PLXNA3
plexin A3
chr14_+_105780751 0.106 NM_001100913
NM_015197
PACS2

phosphofurin acidic cluster sorting protein 2

chr1_-_153585504 0.103 NM_080388
S100A16
S100 calcium binding protein A16
chr19_+_42259397 0.102 NM_002483
CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr5_-_72744351 0.101 NM_004472
FOXD1
forkhead box D1
chrX_-_109683457 0.101 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr2_-_217560247 0.101 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr4_+_2794712 0.099 NM_001122681
SH3BP2
SH3-domain binding protein 2
chr19_+_50270068 0.096 NM_014203
NM_130787
AP2A1

adaptor-related protein complex 2, alpha 1 subunit

chr19_+_1941184 0.095 CSNK1G2
casein kinase 1, gamma 2
chrX_+_52928408 0.092 NM_001099684
FAM156A
FAM156B
family with sequence similarity 156, member A
family with sequence similarity 156, member B
chrX_-_21676416 0.091 NM_153270
KLHL34
kelch-like 34 (Drosophila)
chr19_-_46318432 0.090 NM_030785
RSPH6A
radial spoke head 6 homolog A (Chlamydomonas)
chr7_+_91763851 0.090 LOC613126
uncharacterized LOC613126
chr2_+_66666445 0.089 MEIS1
Meis homeobox 1
chr8_-_23540401 0.088 NM_006167
NKX3-1
NK3 homeobox 1
chr1_-_155225137 0.088 NM_006589
NM_198264
FAM189B

family with sequence similarity 189, member B

chr6_+_116782555 0.088 NM_001010919
FAM26F
family with sequence similarity 26, member F
chr20_+_60174816 0.087 NM_001252339
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr16_-_4466607 0.086 CORO7
coronin 7
chr7_+_39989955 0.086 NM_003718
NM_031267
CDK13

cyclin-dependent kinase 13

chr13_+_50018525 0.085 SETDB2
SET domain, bifurcated 2
chr6_+_34204928 0.085 HMGA1
high mobility group AT-hook 1
chr19_-_44008984 0.085 NM_198850
PHLDB3
pleckstrin homology-like domain, family B, member 3
chr2_+_85921413 0.084 NM_006433
NM_012483
GNLY

granulysin

chr11_+_76883823 0.084 MYO7A
myosin VIIA
chr12_+_98987674 0.083 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr2_-_80530943 0.082 LRRTM1
leucine rich repeat transmembrane neuronal 1
chr6_+_39760148 0.082 NM_001201427
DAAM2
dishevelled associated activator of morphogenesis 2
chr4_+_6675798 0.082 LOC93622
Morf4 family associated protein 1-like 1 pseudogene
chr7_+_99425635 0.081 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr1_+_203764802 0.081 ZC3H11A
zinc finger CCCH-type containing 11A
chr5_-_39270708 0.080 NM_001243093
FYB
FYN binding protein
chr17_+_4487833 0.080 NM_001114974
SMTNL2
smoothelin-like 2
chr18_+_21452981 0.080 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr1_+_228353814 0.079 IBA57
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr16_-_2770551 0.078 NM_031948
PRSS27
protease, serine 27
chr9_-_77643024 0.078 C9orf41
chromosome 9 open reading frame 41
chr16_+_31119748 0.078 BCKDK
branched chain ketoacid dehydrogenase kinase
chr10_+_11060105 0.078 CELF2
CUGBP, Elav-like family member 2
chr6_-_84140854 0.077 NM_002395
ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr4_+_6675654 0.077 LOC93622
Morf4 family associated protein 1-like 1 pseudogene
chr2_+_218990735 0.076 NM_001557
CXCR2
chemokine (C-X-C motif) receptor 2
chr14_+_50359724 0.076 NM_001663
ARF6
ADP-ribosylation factor 6
chr6_-_84140758 0.075 ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr7_+_39990108 0.074 CDK13
cyclin-dependent kinase 13
chr17_+_75447325 0.070 SEPT9
septin 9
chr14_-_51561657 0.070 TRIM9
tripartite motif containing 9
chr1_-_76081693 0.070 SLC44A5
solute carrier family 44, member 5
chr19_-_17559375 0.068 NM_001190844
TMEM221
transmembrane protein 221
chr3_+_48264836 0.068 NM_004345
CAMP
cathelicidin antimicrobial peptide
chrX_-_49121171 0.068 NM_001114377
NM_014009
FOXP3

forkhead box P3

chr19_-_2308155 0.068 NM_001101391
LINGO3
leucine rich repeat and Ig domain containing 3
chr9_-_140317650 0.068 EXD3
exonuclease 3'-5' domain containing 3
chr19_+_50270271 0.068 AP2A1
adaptor-related protein complex 2, alpha 1 subunit
chr3_+_12392993 0.067 NM_015869
PPARG
peroxisome proliferator-activated receptor gamma
chr16_+_14726667 0.067 NM_016561
BFAR
bifunctional apoptosis regulator
chr15_-_40633122 0.067 NM_207380
C15orf52
chromosome 15 open reading frame 52
chr11_-_59436366 0.067 PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr1_+_26348308 0.066 EXTL1
exostoses (multiple)-like 1
chr2_+_167744996 0.065 NM_001079810
NM_001199143
NM_152381
XIRP2


xin actin-binding repeat containing 2


chr3_-_27763784 0.064 NM_005442
EOMES
eomesodermin
chr12_-_109251271 0.064 SSH1
slingshot homolog 1 (Drosophila)
chr13_+_47127312 0.064 LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr12_+_123868705 0.064 SETD8
SET domain containing (lysine methyltransferase) 8
chr4_+_2794811 0.064 SH3BP2
SH3-domain binding protein 2
chr2_+_70485204 0.063 NM_016297
PCYOX1
prenylcysteine oxidase 1
chr14_-_93581507 0.063 ITPK1
inositol-tetrakisphosphate 1-kinase
chr10_+_30723050 0.063 MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr1_-_46152183 0.062 NM_021639
GPBP1L1
GC-rich promoter binding protein 1-like 1
chr7_-_91764036 0.062 NM_001146152
CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr1_+_110527432 0.062 AHCYL1
adenosylhomocysteinase-like 1
chr5_-_179051586 0.060 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr16_+_6823809 0.060 NM_001142334
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr21_+_45161343 0.060 PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr22_+_31489343 0.060 SMTN
smoothelin
chr2_-_219696511 0.059 NM_017431
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr11_-_59436488 0.059 NM_152716
PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr8_+_94929082 0.059 NM_018444
NM_001161780
NM_001161779
NM_001161781
PDP1



pyruvate dehyrogenase phosphatase catalytic subunit 1



chr1_-_221915426 0.059 DUSP10
dual specificity phosphatase 10
chr15_+_91428271 0.059 NM_001143783
NM_001143784
FES

feline sarcoma oncogene

chr3_-_151987332 0.059 LOC401093
uncharacterized LOC401093
chr19_+_58978637 0.059 ZNF324
zinc finger protein 324
chr3_-_14988976 0.058 LOC100505641
uncharacterized LOC100505641
chr1_+_19971865 0.057 NM_001204085
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr19_+_10654591 0.056 NM_032885
ATG4D
ATG4 autophagy related 4 homolog D (S. cerevisiae)
chr13_-_27334777 0.055 NM_005288
GPR12
G protein-coupled receptor 12
chr5_-_93077196 0.055 NM_153216
POU5F2
POU domain class 5, transcription factor 2
chr11_-_67188614 0.055 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr20_-_982806 0.055 NM_001029871
NM_001040007
RSPO4

R-spondin 4

chr17_-_79791152 0.054 NM_001093767
NM_207368
FAM195B

family with sequence similarity 195, member B

chr7_-_95025622 0.054 NM_000940
PON3
paraoxonase 3
chr9_-_140317713 0.054 NM_017820
EXD3
exonuclease 3'-5' domain containing 3
chr10_-_101945787 0.054 NM_001100626
ERLIN1
ER lipid raft associated 1
chr20_+_42875943 0.053 GDAP1L1
ganglioside-induced differentiation-associated protein 1-like 1
chr1_+_20465818 0.053 NM_022819
PLA2G2F
phospholipase A2, group IIF
chr20_+_42875905 0.053 NM_024034
GDAP1L1
ganglioside-induced differentiation-associated protein 1-like 1
chr11_-_117102810 0.052 NM_004716
PCSK7
proprotein convertase subtilisin/kexin type 7
chr19_-_54804172 0.052 NM_001172654
NM_006865
LILRA3

LILRA6
leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3

leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr12_-_120703549 0.052 NM_001080855
NM_001243756
NM_002859
PXN


paxillin


chr12_-_53171104 0.052 NM_015848
KRT76
keratin 76
chr19_+_53761544 0.052 NM_173856
VN1R2
vomeronasal 1 receptor 2
chr22_-_29784430 0.051 AP1B1
adaptor-related protein complex 1, beta 1 subunit
chr17_-_7082654 0.051 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr15_+_83776323 0.051 NM_001144903
NM_023003
TM6SF1

transmembrane 6 superfamily member 1

chr20_+_47538211 0.050 NM_006420
ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr20_+_37590969 0.050 NM_001190809
NM_021931
DHX35

DEAH (Asp-Glu-Ala-His) box polypeptide 35

chr20_-_61992516 0.050 NM_000744
CHRNA4
cholinergic receptor, nicotinic, alpha 4
chr1_-_221915393 0.050 DUSP10
dual specificity phosphatase 10
chr16_-_67184822 0.050 NM_033309
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.